Research

The scientific objective of flIMAGIN3D is to synergistically evolve key aspects in FLIM imaging across disciplines by advancing the acquisition of FLIM data and the analysis pipeline, by developing improved platforms that facilitate imaging for a wide range of (bio)medical, chemical and biophysical applications, and by advancing the state-of-the-art in FLIM biosensors. Through real-world biological and biomedical research lines across the partners we can showcase the validity and power of our developments and unify in streamlining FLIM as an accessible and robust tool.

This aim will be achieved by the following Research Objectives (RO):

RO.1

To create, characterise, standardise and test cost-effective platforms adaptability to all of the various user communities, and to enhance existing imaging capabilities [Doctoral Candidates (DC)2, 6, 9]]

RO. 2

Optimise the data acquisition and user-data interface whereby large amounts of data are quickly and correctly acquired, processed and interpreted under control of intelligent software [DCs 1, 7, 8, 10]

RO.3

Establish a library of tools to act as biosensors, perturbers (‘actuators’) and microenvironments to assess biological activities and processes, and interrogate such activity non-invasively and reproducibly. [DCs  3, 4,5, 10]